ERBM4  Program


Wednesday Sept. 10, 2008


8:40-9:00 a.m.

Opening Address: P. Busquin, Member of European Parliament and former EC Commissioner for Research.

                            B. Rentier, ULg, Rector.

                            J. Destine & J.P. Leburton, workshop co-Chairs.


Session I:  Biomolecules in Biological channels (Chairs: J.P. Leburton & J. Destine)

  9:00-  9:30 a.m.   Akeson M. (UCSC) “Coupling DNA Polymerases to Nanopores”.

  9:30-10:00 a.m.   Howorka S.  (U. College London) “Chemical Tags Facilitate the Sensing of Individual DNA Strands with Nanopores” (4.2Mo)

10:00-10:30 a.m.   Movileanu L. (U. Syracuse) “Grabbing single proteins through electrostatic traps”. (5.5Mo)


10:30-10:50 a.m.  Coffee break


10:50-11:20 a.m.  Meller A. (Boston U) “DNA translocation and unzipping dynamics through small solid-state pores” (23Mo)

11:20-11:50 p.m  Winterhalter M. (U. Bremen) “Transport through natural channels in E.coli: ions, sugar & antibiotics” (29Mo)

11:50-12:20 p.m. Auvray L. (U. Evry) “Translocation of partially folded proteins through nanopores.” (1.8Mo)


12:20-14:00 p.m. Lunch break


Session II:  Nanochannels: Transport and Challenges (Chairs: M. Akeson &M. Winterhalter)

  2:00-2:30 p.m.   Di Ventra M. (UCSD) “DNA sequencing via transverse transport: possibilities and fundamental issues” (3.9Mo)

  2:30-3:00 p.m.  Chou S. (Princeton U.)  A Nanogap Detector Inside Nanofluidic Channel for Fast Real-Time Label-Free DNA Analysis” (PDF, 1.2Mo)

  3:00-3:30 p.m.  Mascini M. (U Firenze )Aptamers Ligands for Bioanalytical Application” (4.0 Mo)



  3:30-4:00 p.m.   Coffee break


  4:00-4:30 p.m.    Milton J. (Oxford Nanopore) “The challenges of transforming nanopore science into sequencing technology”

  4:30-5:00 p.m.    Aksimentiev A. (UIUC) “Effective force, electro-osmotic flow and charge inversion in a solid-state nanopore” (20.5Mo)

  5:00-5:30 p.m.    Marziali A. (U. British Columbia) “Synthetic nanopore force spectroscopy” (6.7 Mo)



Thursday Sept 11, 2008


Session III: Solid state nanopores (Chairs: C. Dekker & A.Aksimentiev)

  9:00-  9:30 a.m.   Wanunu M. (Boston U.) “Enhanced capture of DNA molecules in a solid-state nanopore” (0.6Mo)

  9:30-10:00 a.m.   Timp G. (UIUC) “Stretching Genes in a Synthetic Nanopore

10:00-10-30 a.m.  Creus M. (U. Basel) “Protein translocation through artificial nanopores.” (5.1Mo)


10:30-10:50 a.m. Coffee break & poster session


10:50-11:20 a.m.   Keyser U. (U. Leipzig) “Origin of the electrophoretic force on DNA in solid-state nanopores” (2.1Mo)

11:20-11:40 a.m.   Venkatesan U (UIUC) “"Fabrication of low stress, low capacitance Aluminum Oxide Nanopores for  the electronic detection of biomolecules"

11:40- 12:00 a.m.  Kowalczyk S  (TU Delft) “Translocation of DNA-Protein Structures through Solid-State Nanopores” (3.6Mo)

12:00-12:20 p.m.   Van den hout M. (TU Delft) ‘Translocations of single RNA molecules through solid state nanopores”. (2.2Mo)


12:00- 13:30 p.m. Lunch break


Session IV: Ionic transport (Chair: M. Stroscio)

13:30- 200 p.m.   Siwy Z. (UC Irvine) “Ionic Diodes as Biosensors” (1.6Mo)

  2:00- 2:30 p.m.  Gracheva M. (Clarkson U. &UIUC) “Multi-layered semiconductor membranes for tunable ion current and biomolecule manipulation” (3.3Mo)

  2:30- 3:00 p.m.  Melchionna S. (Harvard U.)” Current blockades long biopolymers through nanopores” (7.7Mo)


3:00-3:30 p.m. Coffee break & poster session


Session V: Opto-electronic detection (Chair: S. Chou)

3:30-4:00 p.m.   Ingebrandt S., (Julich) “Fabrication, readout electronics and application of silicon nanowire transistor arrays for electronic detection of biomolecules” (1.3Mo)

4:00-4:30 p.m.   XiaoHui Tang (UCL)  A Nano Interdigitated Gate MOSFET for Direct Protein Detection

4:30-5:00 p.m.   Wagner P. (U. Hasselt)  Diamond-based DNA sensor”

5:00-5:30 p.m.   Remacle J. (FNDP) " Detection of multiple DNA molecules at low concentrations by the use of arrays"



Friday Sept. 12. 2008.


Session VI:  Biomolecule characterization (Chair: D. Flandre)

  9:00- 9:30 a.m.  Stroscio M (UIC) “I-V, Raman, and Electrophoretic Characterization of  DNA: Phononic, Polaronic, and Electronic Properties” (2.8Mo)

  9:30-10:00 a.m   Wagner P. (U. Hasselt)  Diamond-based DNA sensor” (12.7Mo)


10:00-10:20 a.m. Coffee break & poster session


10:20 - 12:20 p.m.  SESSION EPIGENETIC (Chair: J. Martial)

10:2011:05  F. Fuks (ULB) “Mechanisms of Epigenetics in mammals”

11:05- 11:35   H. Stunnenberg (Radbout U.) “(Epi)genomic research in the single molecule sequencing era: single cell analysis the next challenge?


11:35      Closing Address




Poster Sessions


Fully electronic DNA detection with an array of silicon nanowire transistors

X. T. Vu, J. F. Eschermann, R. Stockmann, R. Ghosh Moulick, A. Offenhäusser, S. Ingebrandt*

Institute of Bio- and Nanosystems (IBN-2) and Center of Nanoelectronic Systems for Information Technology, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany



Electronic Characterization of a Protein Layer with Open-gate and Nanowire Field-Effect Transistors

R. Ghosh-Moulick, X. T. Vu, A. Offenhäusser, S. Ingebrandt*

Institute of Bio- and Nanosystems (IBN-2) and Center of Nanoelectronic Systems for Information Technology, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany


Direct measurement of DNA concentration within a closed tube container by UV light transmission and lateral p-i-n photodiode read-out in SOI technology

O. Bulteel1, P. Dupuis1, S. Jeumont2, L.M. Irenge2,3, J.-L. Gala2,3 and D. Flandre 1

1 Université catholique de Louvain, Louvain School of Engineering, Microelectronics Laboratory, Louvain-la-

Neuve, Belgium

2 Université catholique de Louvain, Faculté de Médecine, Center for Applied Molecular Technologies, Brussels,


3 DLD-Bio, Defense Laboratory Department, Brussels, Belgium



Detection of DNA Sequences Using an Alternating Electric Field in a Nanopore Capacitor

Jeffrey Comer, UIUC



SPICE electrical simulation of a DNA strand translocating through a solid-state nanopore

Amandine Leroux (ULg), J. Destiné (ULg), J.-P. Leburton (UIUC)